General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter U2OS TrkC Functional Assay, 2 vials. (93-0464C3)
The PathHunter U2OS TrkC Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TrkC dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TrkC and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Trichophyton interdigitale; 640
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Breast Cancer Cell Panel
For-profit Organizations: For every order of this item, you must work directly with the contributor, MD Anderson Cancer Center to (i) negotiate a research-use license, and/or (ii) have the contributor provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from MD Anderson Cancer Center that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: M.D. Anderson Cancer Center, Office of Technology Commercialization Email: researchtools@mdanderson.org. Once ATCC has received authorization from MD Anderson Cancer Center, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
Discovery Life Sciences Liver Cancer Tx Naive PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Agilent Technologies ARCTICEXPRESS DE3)RP; 10 X 0.1
Enhanced protein folding and solubility of expressed proteins. Dramatically improves expression for GC-rich genomes when codon bias is a problem. Encodes T7 RNA polymerase under control of the lacUV5 promoter.
Medchemexpress LLC ICOS protein, rat (HEK293, Fc) | >95.0% | 50 UG
Recombinant rat ICOS extracellular domain fused to a C-terminal human Fc, produced in HEK293 cells and supplied lyophilized. It is intended for immunology and cell-signaling research, including receptor-ligand binding assays and antibody characterization.
- Recombinant rat ICOS extracellular domain with C-terminal human Fc tag.
- Expressed in HEK293 mammalian cells for native glycosylation.
- Sequence corresponds to residues E21-L142 (accession Q9R1T7-1).
- High purity >95.0% by reducing SDS-PAGE.
- Lyophilized from 0.22 μm filtered PBS, pH 7.4; store at -20°C.
- Available in small research quantities (for example, 50 μg) for assay use.
Amsbio LLC eLuCidate™ HEK 293, TCF/LEF Reporter Cell Line
eLuCidate™ HEK 293 TCF/LEF Reporter Cell Line
Biochain Institute Inc Colon Tumor Matched Pair Tissue Array - 29 colon tumor/adjacent normal pairs. Plus positive control and negative control, 2 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
Discovery Life Sciences Myelofibrosis Tx Naive PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences Ankylosing Spondylitis PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Eurofins Discoverx PathHunter CHO-K1 GPR39 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0338C2)
The PathHunter GPR39 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR39 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR39 and EA-tagged β-Arrestin-2. Activation of GPR39 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Breast Tumor Tissue Array - 64 Different Breast tumors. Plus positive control and negative control, 2 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
Promocell GmbH PromoCell NHDF-c 500,000 Human Dermal Fibroblasts, cryopreserved
Primary Normal Human Dermal Fibroblasts (NHDF) are isolated form the dermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs.They can be used for wound healing studies and dermatological research to investigate diseases like scleroderma, fibrosarcoma, fibrosis, xeroderma pigmentosum, and histiocytoma. Moreover, fibroblasts are important for cancer research, tissue regeneration, and tissue engineering studies.
Discovery Life Sciences SCLC Mutation PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
ATCC HTR-8/SVneo; Trophoblast; Human (Homo sapiens)
HTR-8/SVneo is a trophoblast cell line that was isolated in 1992 from the placenta of a 6-to-12-week-old embryo. Cells were derived by transfecting the cells that grew out of chorinic villi explants of human first-trimester placenta with the gene encoding for simian virus 40 large T antigen. These cells exhibit a variety of markers characteristic of extravillous invasive trophoblast cells in situ: insulin-like growth factor (IGF)-II, NDOG-5, proliferating cell nuclear antigen (PCNA), human leukocyte antigen framework antigen (W6/32) and a distinct set of integrins including alpha 1, alpha 3, alpha 5, alpha v and beta 1 subunits and alpha v beta 3/beta 5 vitronectin receptor. They were negative formacrophage marker 63/D3, endothelial cell marker factor VIII and alpha 6 and beta 4 integrin subunits. HTR-8/SVneo cells are useful to study trophoblast and placental biology. This cell line was deposited by C Graham (Queen's University).